Imdex Dosage & Drug Information

Concise Prescribing Info

Contents

Isosorbide-5-mononitrate

Indications/Uses

Prophylaxis & long-term treatment of angina pectoris due to CAD.

Dosage/Direction for Use

Initially 30 mg once daily in the morning for the 1st 2-4 days. Increase to 60 mg once daily thereafter. Max: 120 mg/day.

Administration

May be taken with or without food: May be divided along the score-line. Swallow whole or half tab, do not chew/crush.

Contraindications

Hypovolaemia, hypotension, shock, closed-angle glaucoma, raised intracranial pressure, hypertrophic obstructive cardiomyopathy, aortic stenosis & acute MI. Avoid sildenafil, tadalafil, vardenafil.

Special Precautions

Severe hepatic or renal impairment, hypothyroidism, malnutrition, hypothermia, recent history of MI. Pregnancy & lactation.

Adverse Reactions

Headache, tachycardia, palpitations, orthostatic hypotension.

View ADR Monitoring Form

Drug Interactions

Orthostatic hypotension may occur w/ combined use of Ca-channel blockers, antihypertensives, phenothiazines, TCA & alcohol. Sildenafil, tadalafil, vardenafil.

MIMS Class

Anti-Anginal Drugs

ATC Classification

C01DA14 - isosorbide mononitrate ; Belongs to the class of organic nitrate vasodilators. Used in the treatment of cardiac disease.

Regulatory Classification

P₁

Presentation/Packing

Form

Imdex CR tab 60 mg

Packing/Price

2 × 14's

Imdex

isosorbide mononitrate

Manufacturer:

Duopharma

Distributor:

International Med

Marketer:

Pharmahealth