May either be administered as a slow IV inj over 30 sec or as an IV infusion diluted in 20-50 mL infusion fluid over 5 min.
Adult Prevention of acute/delayed chemo- & radiotherapy-induced nausea & vomiting (CINV & RINV) 1-3 mg (10-40 mcg/kg) prior to start of chemotherapy. Soln should be diluted to 5 mL per mg.
Treatment of acute CINV/RINV 1-3 mg (10-40 mcg/kg). Max: 9 mg over 24 hr. Soln should be diluted to 5 mL per mg.
Post-op nausea & vomiting 1 mg (10 mcg/kg) by slow IV inj. Max: 3 mg over 24 hr.
Childn ≥2 yr Prevention of acute/delayed CINV & treatment of acute CINV 10-40 mcg/kg (up to 3 mg) administered as an IV infusion, diluted in 10-30 mL infusion fluid over 5 min prior to start of chemotherapy. One additional dose may be administered at least 10 min after the initial dose (w/in 24-hr period) if required.
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