Cyclofem Dosage & Drug Information

Concise Prescribing Info

Contents

Per 0.5 mL Medroxyprogesterone acetate 25 mg, estradiol cypionate 5 mg

Indications/Uses

Prevention of pregnancy.

Dosage/Direction for Use

IM inj every 28-30 days, not to exceed 33 days.

Contraindications

Known or suspected pregnancy; thrombophlebitis or thromboembolic disorders; past history of deep vein thrombophlebitis or thromboembolic disorders; cerebral vascular or CAD; undiagnosed abnormal genital bleeding; liver dysfunction or disease; carcinoma of the endometrium, breast or other known or suspected estrogen-dependent neoplasia; heavy smoking (≥15 cigarettes/day) & >35 yr; severe HTN; diabetes w/ vascular involvement; headaches w/ focal neurological symptoms; valvular heart disease w/ complications. Pregnancy.

Special Precautions

Annual physical exam is advised. Wt change, lipid disorders, impaired liver function, fluid retention, emotional disorders. Wearers of contact lenses. Lactation.

Adverse Reactions

Arterial thromboembolism, cerebral hemorrhage, cerebral thrombosis, gallbladder disease, hepatic adenomas or benign liver tumors, HTN, MI, pulmonary embolism, thrombophlebitis. Abdominal pain, acne, alopecia, amenorrhea, asthenia, breast tenderness/pain, decreased libido, depression, dizziness, dysmenorrhea, emotional lability, enlarged abdomen, headache, menorrhagia, metrorrhagia, nausea, nervousness, vag moniliasis, vulvovag disorder, wt gain.

View ADR Monitoring Form

Drug Interactions

Aminoglutethamide, rifampin, anticonvulsants, St. John's wort, ascorbic acid, acetaminophen, phenylbutazone.

MIMS Class

Depot Contraceptives

ATC Classification

G03AA17 - medroxyprogesterone and estradiol ; Belongs to the class of progestogens and estrogens in fixed combinations. Used as systemic contraceptives.

Regulatory Classification

P₁S₁S₃

Presentation/Packing

Form

Cyclofem inj

Packing/Price

0.5 mL x 20 × 1's ($600/box)

Cyclofem

Manufacturer:

PT Tunggal

Distributor:

Cordial Trading

Primal