Acyclovir 200 HSV infections Adult & childn >2 yr 1 tab 5 times daily every 4 hr.
Childn <2 yr ½ of adult dosage.
Renal impairment, CrCl <10 mL/min/1.73 m2 1 tab bd every 12 hr.
Prophylaxis of severe forms & very frequently recurring genital HSV infection Immunocompetent patient 1 tab qds every 6 hr. Alternatively, 1 tab tds every 8 hr, or 1 tab bd every 12 hr.
Immunocompromised patient 1 tab qds every 6 hr.
Severely immunocompromised patient (eg, following organ transplant) 2 tab qds every 6 hr.
Acyclovir 400 Shingles Adult 2 tab 5 times daily every 4 hr.
Renal impairment, CrCl 10-25 mL/min/1.73 m2 2 tab tds every 8 hr.
CrCl <10 mL/min/1.73 m2 2 tab bd every 12 hr.
Prevention of HSV infection Severely immunocompromised patient exposed to an elevated risk of infection 1 tab qds every 6 hr.
Acyclovir 800 Shingles Adult 1 tab 5 times daily every 4 hr.
Renal impairment, CrCl 10-25 mL/min/1.73 m2 1 tab tds every 8 hr.
CrCl <10 mL/min/1.73 m2 1 tab bd every 12 hr.
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