5 mg no more than once per night & w/in a few min before going to bed, w/ at least 7 hr remaining before the planned time of awakening. May be increased to 10 mg once daily if dose is well-tolerated but greater effect is needed. Max: 10 mg once daily. Moderate hepatic impairment & co-administration w/ weak CYP3A inhibitors Max: 5 mg once daily.
Avoid alcohol consumption; concomitant use w/ moderate or strong CYP3A inhibitors & inducers. Patients w/ COPD or moderate to severe obstructive sleep apnea. May impair daytime wakefulness. Advice patients about the potential next-day somnolence. Not recommended to use w/ other drugs for insomnia. Individuals w/ history of abuse or addiction to alcohol or other drugs. May impair ability to drive & use machines. Not recommended in severe hepatic impairment. Pregnancy. Not to be used during lactation. Not recommended in ped patients (<18 yr).
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