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Treatment and Prevention of Recurrence of Depression: Initial Dosage: 50 mg once daily is recommended. Upward titration (in 50-mg increments at intervals of at least 1 week) to a maximum daily dosage of 200 mg may be advised in patients who do not respond to 50 mg daily.
Same dosage regimen is effective for treatment of patients with obsessive-compulsive disorder (OCD).
Although dosage adjustments are not required in elderly patients, sertraline should be administered with caution in patients with renal or hepatic impairment.
