Ziomycin Dosage/Direction for Use

Dosage: Children over 45 kg body weight and adults, including elderly patients: The total dose of azithromycin is 1500 mg which should be given over three days (500 mg once daily).
In uncomplicated genital infections due to Chlamydia trachomatis, the dose is 1000 mg as a single oral dose. For susceptible Neisseria gonorrhoeae the recommended dose is 1000 mg or 2000 mg of azithromycin in combination with 250 or 500 mg of ceftriaxone according to local clinical treatment guidelines. For patients who are allergic to penicillin and/or cephalosporins, prescribers should consult local treatment guidelines.
Paediatric population: In children under 45 kg body weight: Ziomycin are not suitable for children under 45 kg.
Renal impairment: No dose adjustment is necessary in patients with mild to moderate renal impairment (GFR 1080 ml/min). Caution should be exercised when azithromycin is administered to patients with severe renal impairment (GFR < 10 ml/min) (see Precautions and Pharmacology: Pharmacokinetics under Actions).
Hepatic impairment: Since azithromycin is metabolised in the liver and excreted in the bile, the drug should not be given to patients suffering from severe liver disease. No studies have been conducted regarding treatment of such patients with azithromycin (see Precautions).
Method of administration: Ziomycin are for oral administration only and should be given as a single daily dose. In common with many other antibiotics Ziomycin should be taken at least 1 hour before or 2 hours after food.