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Hypercalcaemia of Malignancy: Xolnic (Zoledronic Acid) Injection is indicated for the treatment of hypercalcaemia of malignancy following adequate saline rehydration.
Vigorous saline hydration, an integral part of Hypercalcaemia therapy, should be initiated promptly and an attempt should be made to restore the urine output to about 2 L/day throughout treatment.
Multiple Myeloma and bone metastases of solid tumors: Also used in the treatment of multiple myeloma, bone metastases from solid tumors, in conjunction with standard antineoplastic therapy.
The safety and efficacy of Zoledronic acid in the treatment of Hypercalcaemia associated with hyperparathyroidism or with other non-tumor related conditions have not been established.
