Diabetes mellitus
Adult: 200-300 mcg tid.
Elderly: Initiate at lower doses.
Elderly: Initiate at lower doses.
Indications and Dosage
Oral
Diabetes mellitus Adult: 200-300 mcg tid.
Elderly: Initiate at lower doses. |
Administration
Should be taken with food. Take just before meals.
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Contraindications
Inflammatory bowel disease; GI obstruction or patients predisposed to it; conditions which may deteriorate as a result of increased gas formation eg, hernia; severe ketosis; diabetic coma or pre-coma; severe infection; hypersensitivity; pregnancy; lactation. Not to be used as monotherapy in IDDM.
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Special Precautions
History of laparotomy or ileus. Roemheld's syndrome, stenosis, severe hepatic or renal impairment. Child <18 yr; elderly. Monitor LFT. Treat hypoglycaemic episodes with glucose (not with sucrose).
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Adverse Reactions
Flatulence; abdominal distension; diarrhoea; pain; skin reactions; hypoglycemia; increased LFT.
Potentially Fatal: Hepatotoxicity. |
Drug Interactions
May enhance effects of other antidiabetics including insulin.
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Action
Description: Voligbose has general properties similar to acarbose and selectively inhibits α-glucosidase in the enteric canal, delaying the digestion and absorption of carbohydrate, thereby suppressing sharp increase in post-prandial plasma glucose.
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Storage
Store below 30°C.
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MIMS Class
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