Victoza

Victoza

liraglutide

Manufacturer:

Novo Nordisk

Distributor:

DKSH
Concise Prescribing Info
Contents
Liraglutide
Indications/Uses
Monotherapy or in addition to other drugs in adults, adolescents & childn ≥10 yr w/ insufficiently controlled type 2 DM, as an adjunct to diet & exercise. Prevention of major adverse CV events (MACE) in adults w/ type 2 DM at high CV risk, as an adjunct to standard of care therapy.
Dosage/Direction for Use
SC Initially 0.6 mg daily. Increased to 1.2 mg after at least 1 wk. Can be increased to 1.8 mg after at least 1 wk to further improve glycaemic control. Max daily dose: 1.8 mg.
Administration
May be taken with or without food: Inject preferably at the same time of the day.
Contraindications
Special Precautions
Not to be administered by IV or IM. Not to be used in patients w/ type 1 DM or diabetic ketoacidosis. Not a substitute for insulin. Not recommended in patients w/ CHF NYHA class IV; inflammatory bowel disease & diabetic gastroparesis. Discontinue if pancreatitis is suspected. Thyroid AR (eg, goitre) particularly in preexisting thyroid disease. May increase risk of hypoglycaemia in combination w/ sulfonylurea or insulin. Potential risk of dehydration. May affect ability to drive & use machines. Not recommended in patients w/ end-stage renal disease & severe hepatic impairment. Do not use during pregnancy & lactation. Childn <10 yr.
Adverse Reactions
Nausea, diarrhoea. Nasopharyngitis, bronchitis; hypoglycaemia, anorexia, decreased appetite; headache, dizziness; increased heart rate; vomiting, dyspepsia, upper abdominal pain, constipation, gastritis, flatulence, abdominal distension & discomfort, GERD, toothache; rash; fatigue, inj site reactions; increased lipase & amylase.
Drug Interactions
May influence absorption of concomitant administered PO medicinal products. Frequently monitor INR w/ warfarin or other coumarin derivatives.
MIMS Class
Antidiabetic Agents
ATC Classification
A10BJ02 - liraglutide ; Belongs to the class of glucagon-like peptide-1 (GLP-1) analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Victoza soln for inj 6 mg/mL
Packing/Price
(pre-filled pen) 3 mL x 1's
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