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Gout Flare: An increase in gout flares is frequently observed during initiation of anti-hyperuricemic agents, including Febuxostat. If a gout flare occurs during treatment, Febuxostat need not be discontinued. Prophylactic therapy (i.e., non-steroidal anti-inflammatory drug (NSAID) or colchicine upon initiation of treatment) may be beneficial for up to six months.
Drugs should be used according to the physician's advice on cardiac & stroke patient.
Liver function should be monitored.
Use in Children: Safety and efficacy in children below the age of 12 years have not been studied.
