Potentiation of blood sugar-lowering effect w/ insulin & other oral antidiabetics, ACE inhibitors, allopurinol, anabolic steroids & male sex hormones, chloramphenicol, coumarin derivatives, fluoxetine, MAOIs, miconazole, para-aminosalicylic acid, pentoxifylline (high dose parenteral), phenylbutazone, oxyphenbutazone, quinolones, salicylates, sulfonamides, tetracyclines, β-blockers. Weakening of blood sugar-lowering effect w/ acetazolamide, barbiturates, corticosteroids, diazoxide, diuretics, epinephrine & other sympathomimetic agents, laxatives, oestrogens & progestogens, phenothiazines, phenytoin, rifampicin, thyroid hormones. May potentiate or weaken blood sugar-lowering effect w/ H
2-receptor antagonists, clonidine & reserpine; acute & chronic alcohol intake.
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