Thioctic acid: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Myanmar prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Diabetic neuropathy

Adult: 600 mg daily. May also be given via IV admin.

Administration

Should be taken on an empty stomach. Take 30 min before meals. Swallow whole, do not chew/crush.

Special Precautions

Pregnancy, lactation. Monitor blood glucose and adjust diabetic medication accordingly. May cause insulin autoimmune syndrome in diabetics.

Adverse Reactions

Allergic reactions such as skin rash, nausea, hypoglycemia.

Action

Description: Thioctic acid, or α-lipoic acid, is used for its antioxidant effects in the treatment of diabetic neuropathy. It has been tried in the treatment of liver dysfunction and in subacute necrotising encephalopathy. Thioctic acid and its reduced metabolite form a redox couple and may scavenge a wide range of reactive oxygen species.
Pharmacokinetics:
Distribution: Cross the blood brain barrier.

MIMS Class

Nootropics & Neurotonics/Neurotrophics / Other Agents Affecting Metabolism

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