Cervical dilatation in the 1st trimester
Adult: 500 mcg infusion over 3-6 hr.
Pregnancy termination in the 2nd trimester
Adult: 100 mcg/hr infusion for up to 10 hrs; if necessary, increase infusion rate up to 500 mcg/hr to a max total dose of 1.5 mg. May be repeated once 12-24 hrs later if unsuccessful.
Adult: Initially, 100 mcg/hr via infusion. May increase to 500 mcg/hr if needed to control bleeding, after which reduce to a maintenance dose of 100 mcg/hr. Not to exceed a total dose of 1.5 mg in 24 hr.