Sporal Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Itraconazole

Indications/Uses

Listed in Dosage.

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Dosage/Direction for Use

Vulvovag candidosis 2 cap bd for 1 day or 2 cap once daily for 3 days. Pityriasis versicolor 2 cap once daily for 1 wk. Dermatophytosis & oral candidosis 1 cap once daily for 15 days. Tinea pedis, tinea manus 2 cap bd for 1 wk or 1 cap daily for 30 days. Fungal keratitis 2 cap once daily for 3 wk. Aspergillosis 2 cap daily for 2-5 mth. Increased to 2 cap bd in disseminated or invasive cases. Candidosis 1-2 cap daily for 3 wk-7 mth. Non-meningeal cryptococcosis 2 cap daily for 2 mth-1 yr. Cryptococcal meningitis 2 cap bid for 2 mth-1 yr. Maintenance therapy: (meningeal cases) 2 cap once daily. Histoplasmosis 2 cap once-bd for 8 mth. Sporotrichosis 1 cap daily for 3 mth. Paracoccidioidomycosis 1 cap daily for 6 mth. Chromomycosis 1-2 cap daily for 6 mth. Blastomycosis 1 cap daily to 2 cap bd for 6 mth.

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Overdosage

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Administration

Should be taken with food: Take immediately after a full meal.

Contraindications

Hypersensitivity.

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Special Precautions

Known history of liver disease or liver toxicity w/ other drugs. Liver function tests should be carried out mthly for therapy >30 days. Renal impairment. Pregnancy & lactation. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Nausea, abdominal pain, headache, dyspepsia, epigastralgia.

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Drug Interactions

Reduced oral bioavailability w/ rifampicin & phenytoin. Reduce dosage of cyclosporin A, warfarin & digoxin. Terfenadine & astemizole.

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Action

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MIMS Class

Antifungals

ATC Classification

J02AC02 - itraconazole ; Belongs to the class of triazole and tetrazole derivatives. Used in the systemic treatment of mycotic infections.

Regulatory Classification

POM

Presentation/Packing

Form

Sporal cap 100 mg

Packing/Price

100's;4's

Sporal

itraconazole

Manufacturer:

Janssen-Cilag

Distributor:

DKSH