Skelemus Special Precautions

Eperisone Hydrochloride Sustained Release capsules 150mg should be administered with caution in acid-peptic disease, impaired renal or liver functions, blood dyscrasias, and hypersensitivity to aspirin or other NSAIDs. Since weakness, lightheadedness, sleepiness or other symptoms may occur with Eperisone Hydrochloride, the patients should be cautioned against engaging in potentially hazardous activities requiring alertness eg, operating machinery or driving a car. Data on safety and efficacy of Eperisone Hydrochloride in children is not adequate. Lower dose of Eperisone Hydrochloride is advocated in the elderly. Avoid alcoholic beverages whilst taking Eperisone Hydrochloride Sustained Release capsules 150mg. It must be coadministered with methocarbamol with due precaution.
Methacarbamol, aspirin, methotrexate, digoxin, cyclosporin, angiotensin converting enzyme (ACE) inhibitors, diuretics, lithium and warfarin are to be coadministered with due precaution with Eperisone Hydrochloride Sustained Release capsules 150mg.
Effects on ability to drive and use machines: Patients taking Eperisone Hydrochloride Sustained Release capsules 150mg should be cautioned against engaging in potentially hazardous activities requiring alertness eg, operating machinery or driving a car.
Use in Children: Safety in children has not been established (insufficient clinical experience).