Like all medicines, SALACLAV can cause side effects, although not everybody gets them. The following side effects may happen with this medicine.
Conditions the patient need to look out for: Allergic reactions: Skin rash; Inflammation of blood vessels (vasculitis) which may be visible as red or purple raised spots on the skin, but can affect other parts of the body; Fever, joint pain, swollen glands in the neck, armpit or groin; Swelling, sometimes of the face or mouth (angioedema), causing difficulty in breathing; Collapse.
Contact a doctor immediately if any of these symptoms appears. Stop taking SALACLAV.
Inflammation of large intestine: Inflammation of the large intestine, causing watery diarrhoea usually with blood and mucus, stomach pain and/or fever.
Contact the doctor as soon as possible for advice if any of these symptoms appears.
Common side effects (may affect up to 1 in 10 people): Thrush (candida - a yeast infection of the vagina, mouth or skin folds); Diarrhoea.
Uncommon side effects (may affect up to 1 in 100 people): Skin rash, itching; Raised itchy rash (hives); Feeling sick (nausea), especially when taking high doses (if affected take SALACLAV before food); Vomiting; Indigestion; Dizziness; Headache.
Uncommon side effects that may show up in the blood tests: Increase in some substances (enzymes) produced by the liver.
Rare side effects (may affect up to 1 in 1000 people): Skin rash, which may blister, and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge - erythema multiforme).
If any of these symptoms appears contact the doctor urgently: Swelling and redness along a vein which is extremely tender when touched.
Rare side effects that may show up in the blood tests: Low number of cells involved in blood clotting; Low number of white blood cells.
Other side effects: Other side effects have occurred in a very small number of people but their exact frequency is unknown: Allergic reactions (see as previously mentioned).
Inflammation of the large intestine (see as previously mentioned).
Serious skin reactions: A widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), and a more severe form, causing extensive peeling of the skin (more than 30% of the body surface - toxic epidermal necrolysis).
Widespread red skin rash with small pus-containing blisters (bullous exfoliative dermatitis).
A red, scaly rash with bumps under the skin and blisters (exanthemous pustulosis).
Contact a doctor immediately if any of these symptoms is present: Inflammation of the liver (hepatitis); Jaundice, caused by increases in the blood of bilirubin (a substance produced in the liver) which may make the skin and whites of the eyes appear yellow; Inflammation of tubes in the kidney; Blood takes longer to clot; Convulsions (in people taking high doses of SALACLAV or who have kidney problems).
Side effects that may show up in the blood or urine tests: Severe reduction in the number of white blood cells; Low number of red blood cells (haemolytic anaemia); Crystals in urine.
If any side effects are present or if any of the side effects become severe or troublesome, talk to the doctor or nurse. This includes any side effects not listed in this monograph.