Ryzodeg FlexTouch

Ryzodeg FlexTouch

Manufacturer:

Novo Nordisk

Distributor:

DKSH
Concise Prescribing Info
Contents
Per mL 100 u of insulin degludec/insulin aspart in the ratio 70/30 (equiv to 2.56 mg insulin degludec, 1.05 mg insulin aspart)
Indications/Uses
DM in adults, adolescents & childn from 2 yr.
Dosage/Direction for Use
SC Individualized dose. Type 2 DM Initially 10 u followed by individual dose adjustments. Type 1 DM Initially 60-70% of total daily insulin requirements once daily in combination w/ short-/rapid-acting insulin followed by individual dose adjustments.
Special Precautions
Not to be administered IV or IM. Not to be used in insulin infusion pumps. Inadequate dosing &/or discontinuation of treatment may lead to hyperglycaemia & diabetic ketoacidosis. Concomitant illness especially infections & fever; diseases affecting the adrenal, pituitary or thyroid gland. Temporary worsening of diabetic retinopathy due to intensification of insulin therapy w/ abrupt improvement in glycaemic control. May cause insulin Ab to form. Transfer from other insulin medicinal products. Risk of cardiac failure in combination w/ thiazolidinediones. May impair ability to drive a car or use machines due to hypoglycaemia. Kidney or liver diseases. Pregnancy & lactation. Childn 2-5 yr.
Adverse Reactions
Drug Interactions
Reduced insulin requirement w/ oral antidiabetics, GLP-1 receptor agonists, MAOIs, β-blockers, ACE inhibitors, salicylates, anabolic steroids & sulfonamides. Increased insulin requirement w/ OCs, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone & danazol. May mask symptoms of hypoglycaemia w/ β-blockers. Increased/decreased insulin requirements w/ octreotide/lanreotide. May intensify or reduce hypoglycaemic effect of insulin w/ alcohol.
MIMS Class
Insulin Preparations
ATC Classification
A10AD06 - insulin degludec and insulin aspart ; Belongs to the class of intermediate-acting combined with fast-acting insulins and analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Ryzodeg FlexTouch soln for inj 100 u/mL
Packing/Price
3 mL x 1's;3 mL x 5 × 1's
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