Rociverine: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Myanmar prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Smooth muscle spasms

Adult: 30-40 mg daily.

Rectal
Smooth muscle spasms

Adult: 50-75 mg daily.

Contraindications

Prostatic enlargement, paralytic ileus, pyloric stenosis, angle-closure glaucoma.

Special Precautions

Ulcerative coliltis, diarrhoea, myasthenia gravis, thyrotoxicosis, heart failure, acute MI, children and elderly. May cause confusion.

Adverse Reactions

Mouth dryness, difficulty in swallowing and talking, thirst, reduced bronchial secretions, mydriasis with loss of accommodation (cycloplegia) and photophobia, skin flushing and dryness, transient bradycardia followed by tachycardia, palpitations and arrhythmias, difficulty in micturition, reduction in the tone and motility of the GI tract leading to constipation.

Drug Interactions

Effects enhanced when used with drugs that have antimuscarinic properties. May affect the absorption of certain drugs. May also antagonise the effects of metoclopramide, domperidone and cisapride.

Action

Description: Rociverine is an anticholinergic agent that is used as a smooth muscle relaxant.

MIMS Class

Antispasmodics

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