Oral administration of acetylcysteine up to dosage of 25 mg/kg/day. In analogy to preclinical examinations, increased salivation, retching, vomiting and a drop in blood pressure may occur following extreme overdosage. Acute measures eg, instituting vomiting and gastric lavage are not generally indicated and are only to be considered following extreme overdose. A symptomatic therapy is recommended.
Brief restlessness and diarrhoea have been reported. Ambroxol has been tolerated well on oral administration up to a dosage of 25 mg/kg/day.