Promegestone: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Myanmar prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Mastalgia, Menstrual disorders, Progestogen component of menopausal hormonal replacement therapy

Adult: 125-500 mcg daily on a cyclical basis.

Contraindications

Undiagnosed vag bleeding, severe hepatic impairment, pregnancy testing. Pregnancy. History or current high risk of arterial disease.

Special Precautions

CV or renal impairment, diabetes mellitus, asthma, epilepsy, migraines, history of depression, conditions which may be aggravated by fluid retention. Lactation.

Adverse Reactions

GI disturbances, changes in appetite or weight, oedema, acne, chloasma, breast changes, hirsutism, headache, insomnia, altered menstrual cycles, breakthrough bleeding. Alterations in serum lipid profile.

Drug Interactions

Enzyme-inducing drugs may enhance clearance. May inhibit ciclosporin metabolism.

Action

Description: Promegestone is a progestogen structurally related to progesterone.

MIMS Class

Oestrogens, Progesterones & Related Synthetic Drugs

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