Sign Out
Preterax 2.5 mg: The usual dose is one Preterax 2.5 mg/0.625 mg film-coated tablet per day as a single dose, preferably to be taken in the morning and before a meal. If blood pressure is not controlled after one month of treatment, the dose can be doubled.
Preterax 5 mg: One Preterax 5 mg/1.25 mg film-coated tablet per day as a single dose, preferably to be taken in the morning, and before a meal.
When possible, individual dose titration with the components is recommended. Preterax 5 mg/1.25 mg film-coated tablet should be used when blood pressure is not adequately controlled on Preterax 2.5 mg/0.625 mg film-coated tablet. When clinically appropriate, direct change from monotherapy to Preterax 5 mg/1.25 mg film-coated tablet may be considered.
Preterax 10 mg: One Preterax 10 mg/2.5 mg tablet per day as a single dose, preferably to be taken in the morning, and before a meal.
Elderly: Treatment should be started at the normal dose of 1 tab/day.
Patients with Renal Insufficiency: (See Precautions.) In cases of severe renal insufficiency (creatinine clearance <30 mL/min), treatment is contraindicated. In patients with creatinine clearance ≥30 mL/min and <60 mL/min, it is recommended to start the treatment at the dose of 1 Preterax 2.5 mg tab/day, to be taken in the morning.
It is not necessary to change the dose when the creatinine clearance is >60 mL/min. The normal medical practice includes periodic control for creatinine and potassium.
