Allergic rhinitis, Asthma
Adult: 225 mg bid.
Child: 3.5 mg/kg bid. Max dose: 10 mg/kg/day (not exceeding 450 mg daily).
Child: 3.5 mg/kg bid. Max dose: 10 mg/kg/day (not exceeding 450 mg daily).
Indications and Dosage
Oral
Allergic rhinitis, Asthma Adult: 225 mg bid.
Child: 3.5 mg/kg bid. Max dose: 10 mg/kg/day (not exceeding 450 mg daily). |
Contraindications
Acute asthma attacks; hepatic impairment/cirrhosis.
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Special Precautions
Renal impairment. Possible elevations in liver enzymes. Withdraw treatment in patients showing signs consistent with Churg-Strauss syndrome.
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Adverse Reactions
Headache, increased incidence of resp tract infection, GI disturbances, induced generalised pain, fever, myalgia, arthralgia.
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Drug Interactions
Concurrent use with warfarin and other anticoagulants may cause an increase in prothrombin time.
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Action
Description: Pranlukast is a selective leukotriene D4-receptor antagonist. It suppresses early and late bronchoconstrictor responses to inhaled antigen or irritants.
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MIMS Class
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