Sign Out
The combined treatment with narcotics (morphine, meperidine, fentanyl), opioids and tranquilizer (benzodiazepines, barbitals, chloral hydrate, droperidol, etc) is likely to decrease the inducing dosage. These preparations are likely to increase anaesthetic effect of Pofol and to decrease systolic, diastolic, average blood pressure and cardiac output.
In case adjuvants of anaesthesia (nitrous oxide, opioids) are used, the rates of infusion of Pofol should be decreased or controlled during maintenance of anaesthesia. Powerful inhalation anaesthetics (isoflurane, enflurane, halothane) may increase the anaesthetic effect of Pofol and its effect on cardiac and respiratory system.
Pofol has not caused any clinical changes on the action, maintenance degree of the neuromuscular blockers (suxamethonium and nondepolarizing muscle relaxants).
