Hypersensitivity to propofol and to any of the components of Pofol.
Use in pregnancy & lactation: The migration of Pofol to foetus was reported; Pofol should not be used in pregnancy and lactation.
Pofol crosses the placenta and may be associated with neonatal depression. It should not be used for obstetric anaesthesia.
Excretion of Pofol in milk was reported and safety to the neonates has not been established. The use of Pofol in lactation is not recommended and if necessary, lactation should be discontinued.
Use in children: The safety and efficacy of Pofol in children is not established; use in children <3 years is not recommended. Pofol is not recommended for sedation in children, and for maintenance of anaesthesia in children <3 years.