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Patients should be closely monitored for any anginal symptoms (e.g., chest pain), since treatment with cilostazol may increase pulse rate, which could induce angina pectoris.
[A significant increase in PRP (pressure rate product) was observed during long-term administration of cilostazol in a clinical study to evaluate the drug's efficacy in the prevention of recurrence of cerebral infarction]. In clinical trials, angina pectoris was reported in patients treated with the drug.
