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As with other antiplatelet agents, clopidogrel should be used with caution in patients who may be at risk of increased bleeding from trauma, surgery or other pathological conditions. If a patient is to undergo elective surgery and an antiplatelet effect is not desired, clopidogrel should be discontinued 7 days prior to surgery.
Use in pregnancy & lactation: There are no adequate and well-controlled studies in pregnant women. Clopidogrel should be used during pregnancy only if clearly needed.
It is not known whether clopidogrel is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue clopidogrel, taking into account the importance of the drug to the nursing woman.
