Adults and Children >12 Years: The recommended adult dose is 200-400 mg daily given either as a single or in divided doses. Usual Treatment Course: 5-14 days.
Lower Respiratory Tract Infections: 400 mg daily is recommended.
Upper Respiratory Tract Infections and Uncomplicated Urinary Tract Infections: 200 mg once daily is usually effective.
Sinusitis: Therapeutic dosage must be administered for 10-14 days.
Treatment of Uncomplicated Gonorrhoea: The recommended dosage is 400 mg as single dose.
Renal Impairment: Cefixime may be administered in the presence of impaired renal function. Normal dose and schedule may be given in patients with creatinine clearance (CrCl) >20 mL/min.
In patients whose CrCl <60 mL/min, it is recommended that a dose of 200 mg once daily should not be exceeded.
The dose and regimen for patients who are maintained on chronic ambulatory peritoneal dialysis or haemodialysis should follow the same recommendation as that for patients with CrCl <20 mL/min.
Elderly: May be given the same dose as recommended for adults. Renal function should be assessed and dosage should be adjusted in severe renal impairment.