Mycotic diseases of the skin, hair and nails due to Microsporum, Trichophyton, or Epidermophyton respond to griseofulvin therapy.
It must be stressed that, since other fungal diseases are not affected by the medicine, careful mycological study with identification of the responsible organism is the only basis on which therapy can be selected accurately.
Also infections of the hair (tinea capitis) caused by M. canis, M. audouini, T. schoenleini, and T. verrucosum; "ringworm" of the glabrous skin; tinea cruris and tinea corporis caused by M. canis, T. rubrum, T. verrucosum and E. floccosum; and tinea of the hands (T. rubrum, T. mentagrophytes) and beard (Trichophyton species) are readily treatable with griseofulvin.
Griseofulvin also is highly effective in "athlete's foot" or epidermophytosis involving the skin and nails, the vesicular form of which is most commonly due to T. mentagrophytes and the hyperkeratotic type to T. rubrum. Trichophyton rubrum and T. mentagrophytes infections may require higher-than-conventional doses.