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When sulbactam/cefoperazone (1:1) was given subcutaneously to neonatal rats, the reduced testicular weights and immature tubules were seen.
In a domestic study (2001), drug tolerance has been reported in 3% of Escherichia coli, 7% of Klebsiella pneumoniae, 9% of Enterobacter cloacae, 15% of Serratia marcescens, Pseudomonas aeruginosa, 18% of Acinetobacter.
