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Increase of renal disorder has been reported in the concomitant administration of Pacferatam with other cephem drugs or diuretics eg, furosemide. In case of co-administration, pay attention to renal function.
Cephalosporin antibiotics may produce a false positive reaction for glucose in the urine (Benedict's or Fehling's solution or with Clinitest tablets) except Tes-Tape.
Positive direct Coombs' tests have been reported.
A reaction characterized by flushing, sweating, headache and tachycardia has been reported when alcohol was ingested during and as late as the 7th day after cefoperazone administration.
Tetrazol thiomethyl inhibits decomposition of alcohol in liver to induce the accumulation of acetaldehyde followed by flushing, nausea, frequent pulse, sweating and headache.
