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Contraindications
Urinary outflow obstruction, paralytic ileus, myasthenia gravis.
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Special Precautions
Children; elderly; benign prostatic hyperplasia; acute MI, cardiac failure, hypertension, thyrotoxicosis; pregnancy and lactation; fever; angle-closure glaucoma.
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Adverse Reactions
Dryness of mouth, difficulty in talking/swallowing; reduced bronchial secretions; blurring of vision, photophobia; bradycardia followed by tachycardia and arrhythmias; urinary retention, constipation, vomiting, nausea; confusion and giddiness.
Potentially Fatal: Arrhythmias (especially after MI). |
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Drug Interactions
Reduced gastric motility interferes with absorption of other drugs. Effects potentiated by other antimuscarinics including amantadine, some antihistamines, phenothiazines and TCA.
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Action
Description: Oxyphenonium is a quarternary ammonium antimuscarinic.
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MIMS Class
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