Risedronate Sodium (Osteorise) should be taken at least 30 minutes before the first food or drink of the day other than water.
To facilitate delivery to the stomach, Risedronate Sodium (Osteorise) should be swallowed while patient is in an upright position and with a full glass of plain water (6 to 8 oz). Patients should not lie down for 30 minutes after taking the medication.
Patients should receive supplemental calcium and vitamin D if dietary intake is inadequate. Calcium supplements and calcium-, aluminum-, and magnesium-containing medications may interfere with the absorption of Risedronate Sodium (Osteorise) and should be taken at a different time of the day.
Treatment of Postmenopausal Osteoporosis: The recommended regimen is: One 5-mg tablet orally, taken daily.
One 35-mg tablet orally, taken once a week.
Prevention of Postmenopausal Osteoporosis: The recommended regimen is one 5-mg tablet orally, taken daily.
Alternatively, one 35-mg tablet orally, taken once a week may be considered.
Treatment and Prevention of Glucocorticoid-Induced Osteoporosis: The recommended regimen is: One 5-mg tablet orally, taken daily.
Paget's Disease: The recommended treatment regimen is 30 mg orally once daily for 2 months. Re-treatment may be considered (following post-treatment observation of at least 2 months) if relapse occurs, or if treatment fails to normalized serum alkaline phosphatase. For re-treatment, the dose and duration of therapy are the same as for initial treatment. No data are available on more than 1 course of re-treatment.