Pregnancy Category C: Studies in pregnant women or animals are not available. As it is not known whether calcium dobesilate crosses the placental barrier in humans, it should only be administered if the potential benefit justifies the potential risk to the foetus.
Calcium dobesilate enters the maternal milk in very low quantities (0.4 mcg/mL after intake of three 500-mg capsules. As a precaution, either the treatment or the breastfeeding should be stopped.