Isosorbide mononitrate should be used with caution in patients who have a recent history of myocardial infarction or who are suffering from hypothyroidism, hypothermia, malnutrition, and severe liver or renal disease.
Isosorbide mononitrate tablets contain lactose and therefore, it should not be used in patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.
Use in pregnancy: No data have been reported which would indicate the possibility of adverse effects resulting from the use of isosorbide mononitrate in pregnancy.
Use in children: The safety and efficacy in children has not been established.