Hematological effects eg, blood dyscrasias (thrombocytopenia & neutropenia), anemia. Not as substitute for corticosteroids or as treatment for corticosteroids insufficiency. Discontinue w/ occurrence of consistent hepatic dysfunction signs & symptoms, or systemic manifestations (eg, eosinophilia, rash). Do not use in patients w/ aspirin-sensitive asthma. Preexisting asthma. May impair fertility. Monitor for signs & symptoms of GI bleeding. May impair ability to drive & operate machinery. Long-term therapy; risk of cross-reactivity w/ proton pump inhibitor or substituted benzimidazoles. Monitor for potential increase in INR & prothrombin time in concomitant use w/ warfarin. Co-administration w/ atazanavir is not recommended. Aceclofenac: Potentially fatal increased risk of serious CV thrombotic events, MI & stroke. May lead to onset of new or worsening preexisting HTN. Patients w/ CHF or fluid retention. History of ulcer disease or GI bleeding. Risk of renal papillary necrosis & other renal injury w/ long-term use in patients w/ renal impairment, heart failure, liver dysfunction, concurrently using diuretics & ACE-inhibitors, & in the elderly. Not recommended in patients w/ advanced renal disease. Severe hepatic impairment. Do not use in patients w/ aspirin triad. Potentially fatal skin reactions eg, exfoliative dermatitis, Stevens-Johnson syndrome & toxic epidermal necrolysis. Rabeprazole: Not recommended in childn.