Muclear should be used with caution in patients with phenylketonuria (a hereditary metabolic disease) because Muclear contains aspartame as a source of phenylalanine; asthmatic patients; history of peptic ulcer, both because drug-induced nausea and vomiting may increase the risk of gastrointestinal haemorrhage in patients predisposed to the condition and because of a theoretical risk that mucolytics may disrupt the gastric mucosal barrier.
Use in pregnancy & lactation: Muclear should not be used during pregnancy and lactation without medical advice.