May occur stomatitis, nausea, vomiting, fever, rhinorrhea, drowsiness, clamminess, chest tightness, bronchoconstriction. Hypersensitivity reactions have been reported in patients receiving acetylcysteine, including bronchospasm, angioedema, rashes and pruritus, hypotension or occasionally hypertension may occur.
For use as an antidote for acetaminophen overdosage, may result in nausea, vomiting and other gastrointestinal symptoms. Rash (with or without mild fever), pruritus, angioedema, bronchospasm, tachycardia, hypotension and hypertension have occurred.