Sign Out
MOTILIUM-M is contraindicated in the following situations: Known hypersensitivity to domperidone or any of the excipients; Prolactin-releasing pituitary tumor (prolactinoma).
Co-administration with potent CYP3A4 inhibitors which have been shown to cause QT interval prolongation such as, clarithromycin, erythromycin, itraconazole, oral ketoconazole, posaconazole, ritonavir, saquinavir, telithromycin, telaprevir and voriconazole (see Precautions, and Interactions).
Whenever stimulation of gastric motility might be dangerous, e.g., in the presence of gastro-intestinal hemorrhage, mechanical obstruction or perforation.
In patients with moderate or severe hepatic impairment (see Pharmacology: Pharmacokinetics under Actions).
