The recommended dose for Molox tablet is 400 mg once-daily for all indications.
Duration of treatment: The duration of treatment should be determined by the severity of the indication or clinical response. In general, antibiotic therapy should be used for 3-4 days after the manifestations of the infection have cleared. The duration of therapy depends on the type of infection as described below. (See table.)
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In case of community-acquired pneumonia the recommended total treatment duration for sequential administration (intravenous followed by oral) is 7-14 days.
The recommended duration of treatment in skin and soft tissue infections with Molox infusion is 7 days. Therapy may be initial intravenous administration, followed by oral tablet administration when clinically indicated.
Moxifloxacin is administered orally, independent of meals. The tablets are swallowed whole. Patients should be advised to drink fluids liberally and take Moxifloxacin at least 4 hours before or 8 hours after antacids containing magnesium, aluminium, or calcium or multivitamins containing iron or zinc.
Special Populations: Elderly: No adjustment of dosage is required in the elderly.
Children: The use of Moxifloxacin in children and adolescents in the growth phase is contra-indicated.
Hepatic impairment: No dosage adjustment is required in patients with slightly impaired liver function. Moxifloxacin is not recommended in patients with moderate or severe hepatic impairment.
Renal impairment: No dose adjustment is required in patients with any degree of renal impairment (including creatinine clearance ≤30 mL/min/1.73 m2). Moxifloxacin should therefore not be used in patients with advanced renal impairment.
Interethnic differences: No adjustment of dosage is required in ethnic groups.
Gender: Dosage adjustments based on gender are not necessary.