Metergoline: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Myanmar prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Hyperprolactinaemia

Adult: 12 mg daily in divided doses, up to 24 mg daily in hyperprolactinaemic men.

Contraindications

Lactation (discontinue from the 1st day of treatment).

Special Precautions

Pregnancy may occur during treatment for amenorrhoea-galactorrhoea, even without resumption of menstruation. Perform pregnancy test every 20 days and discontinue treatment. Nonhormonal contraceptives may be used.

Adverse Reactions

Nausea, vomiting, insomnia, drowsiness, anxiety, dizziness, weakness.

Action

Description: Metergoline, an ergot derivative, is a dopamine agonist with actions similar to bromocriptine. It is also a serotonin antagonist. It appears to take part in hypothalamic-pituitary neuroendocrine control, stimulating adrenocorticotropic hormone and prolactin release.
Pharmacokinetics:
Absorption: Well-absorbed (oral).
Metabolism: Extensively hepatic.
Excretion: Via faeces (70-80%).

MIMS Class

Antimigraine Preparations / Other Drugs Affecting Hormonal Regulation

Disclaimer: This information is independently developed by MIMS based on Metergoline from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com