Do not use Mabron: if the patient is allergic to tramadol hydrochloride, or any of the other ingredients of this medicine (listed in Description); in acute poisoning with alcohol, sleeping pills, pain relievers or other psychotropic medicines (medicines that affect mood and emotions); if the patient is also taking MAO inhibitors (certain medicines used for treatment of depression) or has taken them in the last 14 days before treatment with Mabron (see "Interactions"); if the patient is an epileptic and the fits are not adequately controlled by treatment; as a substitute in drug withdrawal.