Combinations containing any of the following medications, depending on the amount present, may also interact with LOSAPAC.
Non-steroidal anti-inflammatory drugs (NSAIDs) may antagonise the antihypertensive effect of LOSAPAC.
Concurrent use with sympathomimetics may reduce the antihypertensive effects of LOSAPAC.
Potassium-sparing diuretics, potassium containing medication or potassium supplements used concurrently with LOSAPAC may result in hyperkalaemia since reduction of aldosterone production induced by LOSAPAC may lead to elevation of serum potassium.