Thromboembolism in heparin-induced thrombocytopenia
Adult: Initially, 400 mcg/kg by slow IV inj, followed by a maintenance dose of 150 mcg/kg/hr by continuous IV infusion, adjusted according to response, usually for 2-10 days. Monitor response according to the aPTT ratio to achieve a target of 1.5-2.5. Max infusion rate: 210 mcg/kg/hr.