Latamolol

Latamolol Side Effects

latanoprost + timolol

Manufacturer:

Rafarm

Distributor:

Maxxcare

Marketer:

Mega Lifesciences
Full Prescribing Info
Side Effects
Like all medicines this medicine can cause side effects, although not everybody gets them.
The patient can usually carry on taking the drops, unless the effects are serious. If the patient is worried, talk to a doctor or pharmacist. Do not stop using LATAMOLOL without speaking to the doctor.
Listed as follows are the known side effects of using LATAMOLOL. The most important side-effect is the possibility of a gradual, permanent change in the eye colour. It is also possible that LATAMOLOL might cause serious changes in the way the heart works. If the patient notices changes in the heart rate or heart function they should speak to a doctor and tell them they have been using LATAMOLOL.
The following are known side effects of using LATAMOLOL: Very common effects (may affect more than 1 in 10 people): A gradual change in the eye colour by increasing the amount of brown pigment in the coloured part of the eye known as the iris. If the patient has mixed-colour eyes (blue-brown, grey-brown, yellow-brown or green­ brown) they are more likely to see this change than if they have eyes of one colour (blue, grey, green or brown eyes). Any changes in the eye colour may take years to develop. The colour change may be permanent and may be more noticeable if the patient uses LATAMOLOL in only one eye. There appears to be no problems associated with the change in eye colour. The eye colour change does not continue after LATAMOLOL treatment is stopped.
Common effects (may affect up to 1 in 10 people): Eye irritation (a feeling of burning, grittiness, itching, stinging or the sensation of a foreign body in the eye) and eye pain.
Uncommon effects (may affect up to 1 in 100 people): Headache.
Redness of the eye, eye infection (conjunctivitis), blurred vision, watery eyes, inflammation of the eyelids, irritation or disruption of the surface of the eye.
Skin rashes or itching (pruritus).
Other side effects: Although not seen with latanoprost­-timolol combination, the following additional side effects have been seen with latanoprost and timolol as monotherapy and therefore might occur when the patient uses LATAMOLOL: The following side effects have been seen with latanoprost: Infections and infestations: Developing a viral infection of the eye caused by the herpes simplex virus (HSV).
Immune system disorders: Symptoms of allergic reaction (swelling and redness of the skin and rash).
Psychiatric disorders: Depression, memory loss, decreased sex drive, inability to sleep, nightmares.
Nervous system disorders: Dizziness, tingling or numbness in the skin, changes in blood flow to the brain, worsening of symptoms of myasthenia gravis (if the patient already suffers from this condition), sudden fainting or feeling the patient may faint (syncope).
Eye disorders: Changes to the eyelashes and fine hairs around the eye (increased number, length, thickness and darkening), changes to the direction of eyelash growth, swelling around the eye, swelling of the coloured part of the eye (iritis/uveitis), swelling at the back of the eye (macular oedema), inflammation/irritation of the surface of the eye (keratitis), dry eyes, fluid filled cyst within the coloured part of the eye (iris cyst), light sensitivity (photophobia), sunken eye appearance (deepening of the eye sulcus).
Ear disorders: Whistling/ringing in the ears (tinnitus).
Heart (cardiac) disorders: Worsening of angina, awareness of heart rhythm (palpitations).
Breathing (respiratory) disorders: Asthma, worsening of asthma, shortness of breath.
Skin disorders: Darkening of the skin around the eyes.
Muscle and skeletal disorders: Joint pain, muscle pain.
General disorders: Chest pain.
Like other medicines applied into eyes, LATAMOLOL is absorbed into the blood. The timolol portion of this combination may cause similar side effects as seen with intravenous and/or oral beta-blocking agents. Incidence of side effects after topical ophthalmic application is lower than when medicines are, for example, taken by mouth or injected. Listed side effects include reactions seen within the class of beta-blockers when used for treating eye conditions: Generalized allergic reactions including swelling beneath the skin that can occur in areas such as the face and limbs and can obstruct the airway which may cause difficulty swallowing or breathing, hives or itchy rash, localized and generalized rash, itchiness, severe sudden life­ threatening allergic reaction.
Low blood glucose levels.
Difficulty sleeping (insomnia), depression, nightmares, memory loss.
Fainting, stroke, reduced blood supply to the brain, increases in signs and symptoms of myasthenia gravis (muscle disorder), dizziness, unusual sensations like pins and needles, and headache.
Signs and symptoms of eye irritation (e.g. burning, stinging, itching, tearing, redness), inflammation of the eyelid, inflammation in the cornea, blurred vision and detachment of the layer below the retina that contains blood vessels following filtration surgery which may cause visual disturbances, decreased corneal sensitivity, dry eyes, corneal erosion (damage to the front layer of the eyeball), drooping of the upper eyelid (making the eye stay half closed), double vision.
Slow heart rate, chest pain, palpitations, oedema (fluid build up), changes in the rhythm or speed of the heartbeat, congestive heart failure (heart disease with shortness of breath and swelling of the feet and legs due to fluid build up), a type of heart rhythm disorder, heart attack, heart failure.
Low blood pressure, Raynaud's phenomenon, cold hands and feet.
Constriction of the airways in the lungs (predominantly in patients with pre-existing disease), difficulty breathing, cough.
Taste disturbances, nausea, indigestion, diarrhoea, dry mouth, abdominal pain, vomiting.
Hair loss, skin rash with white silvery coloured appearance (psoriasiform rash) or worsening of psoriasis, skin rash.
Muscle pain not caused by exercise.
Sexual dysfunction, decreased libido.
Muscle weakness/tiredness.
In very rare cases, some patients with severe damage to the clear layer at the front of the eye (the cornea) have developed cloudy patches on the cornea due to calcium build-up during treatment.
If the patient gets any side effects, talk to the doctor or pharmacist. This includes any possible side effects not listed in this monograph.
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