Iron-deficiency anaemia
Adult: As elemental iron: 100-200 mg daily in divided doses. Usual prophylactic dose: 60-120 mg daily.
Indications and Dosage
Oral
Iron-deficiency anaemia Adult: As elemental iron: 100-200 mg daily in divided doses. Usual prophylactic dose: 60-120 mg daily.
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Contraindications
Patients receiving repeated blood transfusions. Oral and parenteral iron therapy should not be used together.
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Special Precautions
Haemochromatosis, haemoglobinopathies; existing GI diseases eg. inflammatory bowel disease, intestinal strictures and diverticulae.
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Adverse Reactions
GI irritation and abdominal pain w/ nausea, vomiting, diarrhoea or constipation.
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Drug Interactions
Compounds containing calcium and magnesium (including antacids and mineral supplements), bicarbonates, carbonates, oxalates, or phosphates, may impair the absorption of iron. Response to iron may be delayed when used w/ systemic chloramphenicol. Iron may decrease absorption of cefdinir, biphosphonates, entacapone, fluoroquinolones, levodopa, methyldopa, mycophenolate mofetil, penicillamine, levothyroxine. Absorption of both agents may be diminished when iron is taken with zinc salts, tetracyclines (separate admin by 2-3 hr), acetohydroxamic acid.
Potentially Fatal: Toxic complexes may form with dimercaprol. |
Action
Description: Iron and iron salts are used for the treatment or prophylaxis of iron-deficiency anaemias. They should not be given for the treatment of other types of anaemia except where iron deficiency is also present. Iron-deficiency anaemias respond readily to iron therapy but the underlying cause of the anaemia should be determined and treated.
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