Invokana Drug Interactions

Tell the doctor or pharmacist if the patient is taking, has recently taken, or might take any other medicines. This is because this medicine can affect the way some other medicines work. Also, some other medicines can affect the way this medicine works.
In particular, tell the doctor if the patient is taking any of the following medicines: other antidiabetics: either insulin or a sulphonylurea (such as glimepiride or glipizide) - the doctor may want to reduce the dose in order to avoid the blood sugar level from getting too low (hypoglycaemia); medicines used to lower the blood pressure (anti-hypertensives), including diuretics (medicines used to remove levels of excess water in the body, also known as water tablets) since this medicine can also lower the blood pressure by removing levels of excess water in the body. Possible signs of losing too much fluid from the body are listed at Side Effects; St. John's wort (a herbal medicine to treat depression); carbamazepine, phenytoin, or phenobarbital (medicines used to control seizures); efavirenz or ritonavir (a medicine used to treat HIV infection); rifampicin (an antibiotic used to treat tuberculosis); cholestyramine (medicine used to reduce cholesterol levels in the blood). See Taking this medicine under Dosage & Administration; digoxin or digitoxin (medicines used for certain heart problems). The level of digoxin or digitoxin in the bleed may need to be checked if taken with Invokana; dabigatran (blood thinner medicine that lowers the risk of blood clot formation).