May cause electrolyte disturbances characterized by HTN, & oedema due to Na & water retention, & increased K excretion, which may cause hypokalaemic alkalosis. Increased susceptibility to infection (eg, sepsis fungal & viral) & delayed wound healing. Cardiac failure. Peptic ulcerations w/ haemorrhage & perforation. Glycosuria; osteoporosis & spontaneous fractures. Increased appetite. Posterior subcapsular cataract. Adrenal cortex atrophy, acute adrenal insufficiency in prolonged treatment. Cushing syndrome. Growth inhibition or arrest in childn. Amenorrhoea. Behavioural disturbances including mental & neurological disturbances. Intracranial HTN. Thrombo-embolic complications; lymphocytopaenia. Myopathy. Hyperglycaemia w/ accentuation or precipitation of diabetic state; increased insulin requirements of diabetics. Hyperhidrosis & aseptic necrosis of bone.