Esme Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Esomeprazole

Indications/Uses

H. pylori +ve duodenal ulcers w/ appropriate antibiotics. Prevention of relapse of gastro-oesophageal reflux. Short-term management of mild functional dyspepsia.

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Dosage/Direction for Use

Adult GERD 20 or 40 mg once daily for 4-8 wk. Prevention of GERD 20 mg once daily. Ulcer related to H. pylori infection 40 mg once daily + amoxicillin 1,000 mg + clarithromycin 500 mg bd for 10 days. Reduction of chance of gastric ulcer in patient taking NSAID 20 or 40 mg once daily. Maintenance for prevention of gastro-oesophageal reflux 20 mg daily for up to 1 yr. Functional dyspepsia 20 mg daily for 2-4 wk. Childn Individualized dosage.

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Overdosage

View Esme overdosage for action to be taken in the event of an overdose.

Administration

Should be taken on an empty stomach: Take at least 1 hr before meals. Swallow whole, do not chew/crush.

Contraindications

Hypersensitivity. Liver impairment. Pregnancy & lactation.

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Special Precautions

Not indicated for mild GI complaints. Exclude possibility of malignant gastric ulcer or oesophageal disease prior to treatment. Childn.

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Adverse Reactions

Nausea, vomiting, diarrhoea, constipation, abdominal pain, dry mouth, glossitis, taste abnormalities, colitis; headache, dizziness, somnolence, insomnia, tremor; skin rash, urticaria, pruritus, alopecia; increased hepatic enzymes; thrombocytopenia, anaemia, leucopenia, neutropenia & eosinophilia; asthenia, fever, oedema, arthralgia, myalgia, gynaecomastia, galactorrhoea, blurred vision.

Drug Interactions

Possible interactions w/ drugs metabolised by cytochrome P450. May reduce conc of warfarin.

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Storage

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Description

View Esme description for details of the chemical structure and excipients (inactive components).

Action

View Esme mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antacids, Antireflux Agents & Antiulcerants

ATC Classification

A02BC05 - esomeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

Regulatory Classification

POM

Presentation/Packing

Form

Esme EC tab 20 mg

Packing/Price

1 × 10's

Form

Esme EC tab 40 mg

Packing/Price

1 × 10's

Esme

esomeprazole

Manufacturer:

Zifam Pinnacle

Distributor:

Pinnacle House