Patients who are allergic to any of its ingredients; have suffered allergic reactions to similar medicinal products; pregnant, suspect that might be, or are breastfeeding; have cardiovascular shock, cardiac insufficiency and have been diagnosed with angina pectoris, myocardial infarction or cerebral infarction in the previous days; suffering from serious renal impairment or are on haemodialysis treatment; suffering from serious liver failure; have diseases caused by narrow heart valves; have narrow renal arteries; children and adolescents.